Activities
The activities of the Consortium will include the following:
- Define a set of appropriate experimental model systems to be used by the Consortium to study various aspects of RTK signaling, including various disease contexts, dynamic properties, spatial regulation and effect of drugs and therapeutic modalities
- Collect, integrate, and improve computational models and analytical methods necessary to study RTK signaling networks
- Create and maintain a distributed database that allows data and model sharing among Consortium members
- Produce and collect the large amounts of high-quality data necessary for modeling and standardize technology and methods needed for data production
- Host a web site for disseminating Consortium results to the general scientific community and providing information on Consortium activities
- Hold workshops in which computational and experimental scientists work together to determine activities necessary to further improve RTK network models
- Hold workshops where scientists and clinicians design research programs that could improve therapies
- Provide cross-disciplinary training courses to improve communication between experimental and mathematical participants and to facilitate their productive interactions
- Communicate with relevant research and advocacy groups such as pharmaceutical industry clinicians and patients to increase their involvement with the Consortium's research program
- Provide an integrated computational platform to the Consortium members for representation, simulation and data handling
- Define the most critical technologies that need to be developed and data that need to be collected
- Promote and coordinate grant applications of members to enhance synergy and complementation, reduce duplication of effort and increase accessibility to expensive core facilities
- Educate a new generation of researchers in the systems biology of RTK signaling and gene networks.
